关键词: 中心静脉导管, 导管相关血流感染, 预测模型, 系统评价, 感染控制, 护理

Abstract:

Objective To systematically evaluate the risk prediction model for central venous catheter-related bloodstream infections and provide references for clinical practice. Methods Databases such as CNKI，Wanfang，CBM，VIP，PubMed，Web of Science，Cochrane Library，etc. were retrieved. The search period is from database establishment to June 2，2023. There are 2 researchers who independently screened and extracted the literature，and evaluated the quality of the literature using bias assessment tools of predictive model risk. Results A total of 9 articles were included，including 9 risk prediction models for catheter-related bloodstream infections. The total sample size was 80~11 901 cases；the number of outcome events was 19~403 cases；the C index of the included model was 0.81~0.93. The area under the curve of the subjects ranged from 0.73~0.90. The predictors that appear more frequently in the model mainly included the history of diabetes，albumin value，the number of days of catheterization，the location of catheterization. The evaluation results of the bias assessment tool of predictive model risk for research show that the overall applicability of the included risk prediction models is good，but the bias risk is high. The reasons are related to the improper source of research sample data，inappropriate processing of continuous variable methods，failure to process missing data，insufficient model performance evaluation，and non-standard evaluation indicators. Conclusion There are still some shortcomings in the risk prediction model for central venous catheter-related bloodstream infections. In the future，the quality of related model research should be further improved，especially in terms of predictive factor analysis，model evaluation indicators，etc.，which should be further standardized.

Key words: Central Venous Catheter, Catheter Related Bloodstream Infection, Prediction Model, Systematic Review, Infection Prevention and Control, Nursing Care