结直肠癌患者报告结局评估工具及临床应用的研究进展

doi:10.3761/j.issn.0254-1769.2022.09.010

摘要/Abstract

摘要：

目前结直肠癌患者的生存时间已逐渐延长,但癌症及治疗会对其带来诸多困扰。结直肠癌患者报告结局注重患者身心体验的评估,有助于医护人员发现其健康困扰,给予针对性处理。该文综述了国内外结直肠癌领域主要的患者报告结局评估工具及其临床应用情况,比较分析了现有工具的内容特点、存在的问题,提出了未来的研究方向,以期为国内结直肠癌患者报告结局评估工具的应用、开发及临床实践提供参考依据。

关键词: 结直肠癌, 患者报告结局, 评估工具, 综述, 护理

Abstract:

Currently,the survival time of colorectal cancer patients has been gradually extended,but cancer and treatment can cause many troubles for them. Patient-reported outcomes with colorectal cancer focus on assessing the physical and psychological experience of patients,which helps to identify their health challenges and give targeted treatment. This article reviews commonly used patient-reported outcome measures in the field of colorectal cancer at home and abroad and their clinical application. The content characteristics,existing problems of the current tools were comparatively analyzed. Future research directions are proposed. It is intended to provide a reference for the application,development,and clinical practice of patient-reported outcome measures for colorectal cancer patients in China.

Key words: Colorectal Neoplasms, Patient-Reported Outcomes, Assessment Tools, Review, Nursing Care

孟祥敏, 王倩, 闫荣, 林雨婷, 丁敏. 结直肠癌患者报告结局评估工具及临床应用的研究进展[J]. 中华护理杂志, 2022, 57(9): 1094-1099.

MENG Xiangmin, WANG Qian, YAN Rong, LIN Yuting, DING Min. Research progress on assessment tools of patient-reported outcomes for colorectal cancer patients and the clinical application[J]. Chinese Journal of Nursing, 2022, 57(9): 1094-1099.

参考文献 40

[1]	Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2021, 71(3):209-249. DOI URL
[2]	Zhang SW, Sun KX, Zheng RS, et al. Cancer incidence and mortality in China,2015[J]. J Natl Cancer Cent, 2021,1(1):2-11.
[3]	van Cutsem E, De Gramont A, Henning G, et al. Improving outcomes in patients with CRC:the role of patient reported outcomes-an ESDO report[J]. Cancers (Basel), 2017,9(6):E59.
[4]	U.S. Department of Health and Human Services FDA Center for Drug Evaluation and Research,U.S. Department of Health and Human Services FDA Center for Biologics Evaluation and Research,U.S. Department of Health and Human Services FDA Center for Devices and Radiological Health. Guidance for industry:patient-reported outcome measures:use in medical product development to support labeling claims:draft guidance[J]. Health Qual Life Outcomes, 2006, 4:79. DOI URL
[5]	Miura Y, Ando M, Yamazaki K, et al. Time-dependent discrepancies between physician-assessed and patient-reported oxaliplatin-induced peripheral neuropathy in patients with metastatic colorectal cancer who received mFOLFOX6 plus bevaci-zumab:a post hoc analysis(WJOG4407GSS2)[J]. Support Care Cancer, 2021, 29(7):3715-3723. DOI PMID
[6]	Carli F, Bousquet-Dion G, Awasthi R, et al. Effect of multimodal prehabilitation vs postoperative rehabilitation on 30-day postoperative complications for frail patients undergoing resection of colorectal cancer:a randomized clinical trial[J]. JAMA Surg, 2020, 155(3):233-242. DOI URL
[7]	Ooki A, Morita S, Iwamoto S, et al. Patient-reported symptom burden as a prognostic factor in treatment with first-line cetuximab plus chemotherapy for unresectable metastatic colorectal cancer:results of phaseⅡ QUACK trial[J]. Cancer Med, 2020, 9(5):1779-1789. DOI URL
[8]	黄跃师, 朱豫琪, 杨瑒, 等. 医护人员对患者报告结局认知和态度的质性研究[J]. 护士进修杂志, 2021, 36(12):1117-1123.
	Huang YS, Zhu YQ, Yang Y, et al. Cognition and attitude of Chinese medical staff on patient-reported outcomes:a qualitative study[J]. J Nurses Train, 2021, 36(12):1117-1123.
[9]	Dawson J, Doll H, Fitzpatrick R, et al. The routine use of patient reported outcome measures in healthcare settings[J]. BMJ, 2010, 340:c186. DOI URL
[10]	McNair AG, Whistance RN, Forsythe RO, et al. Synthesis and summary of patient-reported outcome measures to inform the development of a core outcome set in colorectal cancer surgery[J]. Colorectal Dis, 2015, 17(11):O217-O229.
[11]	Dueck AC, Mendoza TR, Mitchell SA, et al. Validity and reliability of the US national cancer institute’s Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events(PRO-CTCAE)[J]. JAMA Oncol, 2015, 1(8):1051-1059. DOI URL
[12]	Yang SS, Chen L, Liu Y, et al. Validity and reliability of the simplified Chinese Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events[J]. BMC Cancer, 2021, 21(1):860. DOI URL
[13]	Basch E, Dueck AC, Rogak LJ, et al. Feasibility of implementing the Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events in a multicenter trial:NCCTG N1048[J]. J Clin Oncol, 2018:JCO2018788620.
[14]	Cella D, Riley W, Stone A, et al. The Patient-Reported Outcomes Measurement Information System (PROMIS) developed and tested its first wave of adult self-reported health outcome item banks:2005-2008 J Clin Epidemiol, 2010, 63(11):1179-1194. DOI URL
[15]	National Institutes of Health. Intro to PROMIS[EB/OL].(2021-05-10)[2021-08-03]. https://www.healthmeasures.net/explore-mea-surement-systems/promis/intro-to-promis.
[16]	National Institutes of Health. Scoring Instructions[EB/OL]. [2021-10-03]. https://www.healthmeasures.net/score-and-interpret/calculate-scores/scoring-instructions.
[17]	Hedrick TL, Harrigan AM, Thiele RH, et al. A pilot study of patient-centered outcome assessment using PROMIS for patients undergoing colorectal surgery[J]. Support Care Cancer, 2017, 25(10):3103-3112. DOI PMID
[18]	皋文君, 袁长蓉. 患者自我报告结局测量信息系统在国外的应用进展[J]. 中华护理杂志, 2018, 53(11):1401-1405.
	Gao WJ, Yuan CR. Application status of Patient Reported Outcomes Measurement Information System in foreign countries[J]. Chin J Nurs, 2018, 53(11):1401-1405.
[19]	Gujral S, Conroy T, Fleissner C, et al. Assessing quality of life in patients with colorectal cancer:an update of the EORTC quality of life questionnaire[J]. Eur J Cancer, 2007, 43(10):1564-1573. PMID
[20]	Whistance RN, Conroy T, Chie W, et al. Clinical and psychometric validation of the EORTC QLQ-CR 29 questionnaire module to assess health-related quality of life in patients with colorectal cancer[J]. Eur J Cancer, 2009, 45(17):3017-3026. DOI PMID
[21]	Lin JB, Zhang L, Wu DW, et al. Validation of the Chinese version of the EORTC QLQ-CR 29 in patients with colorectal cancer[J]. World J Gastroenterol, 2017, 23(10):1891-1898. DOI URL
[22]	van der Hout A, Neijenhuijs KI, Jansen F, et al. Measuring health-related quality of life in colorectal cancer patients:systematic review of measurement properties of the EORTC QLQ-CR 29[J]. Support Care Cancer, 2019, 27(7):2395-2412. DOI URL
[23]	Blazeby JM, Fayers P, Conroy T, et al. Validation of the European Organization for Research and Treatment of Cancer QLQ-LMC 21 questionnaire for assessment of patient-reported outcomes during treatment of colorectal liver metastases[J]. Br J Surg, 2009, 96(3):291-298. DOI PMID
[24]	Wolstenholme J, Fusco F, Gray AM, et al. Quality of life in the FOXFIRE,SIRFLOX and FOXFIRE-global randomised trials of selective internal radiotherapy for metastatic colorectal cancer[J]. Int J Cancer, 2020, 147(4):1078-1085. DOI PMID
[25]	Ward WL, Hahn EA, Mo F, et al. Reliability and validity of the Functional Assessment of Cancer Therapy-Colorectal (FACT-C) quality of life instrument[J]. Qual Life Res, 1999, 8(3):181-195. PMID
[26]	Yost KJ, Cella D, Chawla A, et al. Minimally important differences were estimated for the Functional Assessment of Cancer Therapy-Colorectal (FACT-C) instrument using a combination of distribution- and anchor-based approaches[J]. J Clin Epidemiol, 2005, 58(12):1241-1251. PMID
[27]	杨铮, 卢玉波, 李云峰, 等. 大肠癌患者生命质量测定量表FACT-C(V4.0)中文版应用评价[J]. 中国组织工程研究与临床康复, 2007, 11(43):8753-8756.
	Yang Z, Lu YB, Li YF, et al. Evaluation of the Functional Assessment of Cancer Therapy-Colorectal(V4.0) in Chinese version[J]. J Clin Rehabilitative Tissue Eng Res, 2007, 11(43):8753-8756.
[28]	Drury A, Payne S, Brady AM. Identifying associations between quality of life outcomes and healthcare-related variables among colorectal cancer survivors:a cross-sectional survey study[J]. Int J Nurs Stud, 2020, 101:103434. DOI URL
[29]	杨铮, 卢玉波, 万崇华, 等. 癌症患者生命质量测定量表体系之大肠癌量表QLICP-CR的研制[J]. 癌症, 2008, 27(1):96-100.
	Yang Z, Lu YB, Wan CH, et al. Development of the system of Quality of Life Instruments for Cancer Patients:Colorectal Cancer(QLICP-CR)[J]. Chin J Cancer, 2008, 27(1):96-100.
[30]	刘敏. 辽宁省结直肠癌患者住院费用和生命质量及其影响因素研究[D]. 沈阳: 中国医科大学, 2019.
	Liu M. Research on hospitalization expenses and quality of life of colorectal cancer patients in Liaoning province and their influencing factors[D]. Shenyang: China Medical University, 2019.
[31]	杨铮. 癌症患者生命质量测定量表共性模块(V2.0)研制及最小临床有意义差异制定[D]. 广州: 南方医科大学, 2015.
	Yang Z. Development of the general module of the system of Quality of Life Instruments for Cancer Patients(V2.0) and estimation of its minimal clinically important difference[D]. Guangzhou: Southern Medical University, 2015.
[32]	Colwell HH, Mathias SD, Turner MP, et al. Psychometric evaluation of the FACT Colorectal Cancer Symptom Index:reliability,validity,responsiveness,and clinical meaningfulness[J]. Oncologist, 2010, 15(3):308-316. DOI PMID
[33]	Temple LK, Bacik J, Savatta SG, et al. The development of a validated instrument to evaluate bowel function after sphincter-preserving surgery for rectal cancer[J]. Dis Colon Rectum, 2005, 48(7):1353-1365. DOI URL
[34]	侯晓婷, 庞冬, 路潜, 等. 肠道功能问卷中文版在直肠癌保肛术后患者中的信效度研究[J]. 中华护理杂志, 2014, 49(12):1453-1458.
	Hou XT, Pang D, Lu Q, et al. Reliability and validity of the MSKCC Bowel Function Instrument in a sample of Chinese rectal cancer patients undergoing sphincter-preserving surgery[J]. Chin J Nurs, 2014, 49(12):1453-1458.
[35]	Yoon BJ, Oh HK, Lee J, et al. Effects of probiotics on bowel function restoration following ileostomy closure in rectal cancer patients:a randomized controlled trial[J]. Colorectal Dis, 2021, 23(4):901-910. DOI URL
[36]	Juul T, Ahlberg M, Biondo S, et al. International validation of the Low Anterior Resection Syndrome Score[J]. Ann Surg, 2014, 259(4):728-734. DOI URL
[37]	Al-Saidi AMA, Verkuijl SJ, Hofker S, et al. How should the Low Anterior Resection Syndrome Score be interpreted[J]. Dis Colon Rectum, 2020, 63(4):520-526. DOI PMID
[38]	Hou XT, Pang D, Lu Q, et al. Validation of the Chinese version of the Low Anterior Resection Syndrome Score for measuring bowel dysfunction after sphincter-preserving surgery among rectal cancer patients[J]. Eur J Oncol Nurs, 2015, 19(5):495-501. DOI URL
[39]	熊燕. Miles术后患者不适反应自我报告量表的构建及其应用研究[D]. 南昌: 南昌大学, 2020.
	Xiong Y. Construction and application of Self-Reporting Scale for Patients with Miles Postoperative Discomfort[D]. Nanchang: Nanchang University, 2020.
[40]	王攀峰, 胡佳慧, 张洪君, 等. 结构化护理风险评估与记录系统的构建与应用[J]. 中华护理杂志, 2018, 53(6):717-719.
	Wang PF, Hu JH, Zhang HJ, et al. Construction and application of the structured nursing risk assessment and recording system[J]. Chin J Nurs, 2018, 53(6):717-719.