Objective To explore and implement a differentiated management strategy for multi-campus hospitals to improve patient experience and satisfaction，and achieve the goal of homogenized management. Methods In December 2021，the Picker Patient Experience Questionnaire was used to survey the patient experience at 3 campuses of a tertiary A hospital in Hangzhou，and the reasons for the differences were analyzed. Based on policy document reviews，special group discussions，and expert meetings，differentiated management strategy for multi-campus hospitals was formulated. The patient experience and satisfaction before（December 2021） and after（December 2023） the implementation were compared. Results After the application of the one-hospital multi-campus difference management strategy，the overall medical experience score of the patients in the 3 campus was（58.54±2.36） points，which was higher than（58.13±3.24） points before the application（t=-3.223，P=0.001），and there was no statistically significant differences among the patients in the 3 campuses（F=0.781，P=0.458）. After the application of the management strategy，the overall satisfaction score of the patients in the 3 campus was（98.44±6.22） points，which was higher than （97.98±6.87） points before the application of the management strategy（t=-2.490，P=0.013），and there was no statistical significance among the patients in the 3 campus（F=1.128，P=0.324）. The number of banners and letters of commendation received by the 3 campuses increased from 1 661 before the application to 2 190 after the application，with a growth rate of 31.85%. Conclusion Differentiated management in a multi-campus hospital，aiming at homogenized quality through differentiated strategies，is practicable and can significantly improve the patient experience and satisfaction across different campuses.
