Objective To evaluate the effect of pneumatic compression devices and short stretch bandages compression therapy on wound healing in patients with leg venous ulcer. Methods Databases such as the Cochrane Library,PubMed,CINAHL,Web of Science,CNKI,Wanfang,VIP and CBM database were searched up to January 20,2021 for randomized controlled trials（RCTs） on the effectiveness of pneumatic compression devices and short stretch bandages compression therapy on wound healing in patients with venous ulcers. According to the inclusion and exclusion criteria,2 researches independently screened each database,extracted data,and assessed the methodological quality of included studies. RevMan 5.3 software was used for meta analysis. Results 6 RCT studies involving 350 patients were included. The meta analysis showed that there was no significant difference of the pneumatic compression devices compared with the short stretch bandage for compression therapy in wound healing rate [RR=0.88,95%CI（0.71,1.09）,P=0.25],change of ulcer size[MD=-3.22,95%CI（-6.73,0.28）,P=0.07],rate of healing[SMD=1.45,95%CI（-0.31,3.21）,P=0.11],and adverse event[RR=0.55,95%CI（0.08,3.75）,P=0.54]. Conclusion Compression therapy for leg venous ulcer patients with pneumatic compression devices can achieve similar effects with short stretch bandage on wound healing rate,change of ulcer size,rate of healing,and adverse event. As all the studies included in this meta-analysis are foreign literature,pilot trials with small samples can be carried out in the future to further evaluate the applicability and feasibility of pneumatic compression therapy in leg venous ulcer patient in China.
