Objective To retrieve,evaluate and summarize the best evidence of resistance training for breast cancer-related lymphedema.Methods We searched BMJ Best Practice,UpToDate,Registered Nurses’ Association of Ontario(RNAO),National Comprehensive Cancer Network(NCCN),National Institute for Health and Clinical Excel-lence(NICE),Scottish Intercollegiate Guidelines Network(SIGN),Medive,PubMed,CINAHL,Cochrane library,Joanna Briggs Institute(JBI) COnNECT+,CNKI,Wanfang,National Lymphedema Network(NLN),International Society of Lymphology(ISL) to collect relevant guidelines,evidence summaries,recommended practice,systematic reviews and expert consensuses published from database construction to September 1st of 2020. 2 researchers evaluated the quality of various literature,and extracted recommendations and research conclusions from the included literature.Results Totally 21 articles were involved,including 1 guideline,14 systematic reviews,2 expert consensuses,1 recommended practice and 3 evidence summaries. Finally,23 pieces of best evidence about contraindications,timing of training,training forms,training intensity and training effectiveness were summarized.Conclusion Resistance training combined with individualized exercises,professional guidance and regular monitoring management is safe and beneficial. Clinical staff should develop resistance training program based on clinical environment as well as patient’s individual situation and training conditions.