Objective To explore the application effect of four-part correction rehabilitation training in patients with vocal cord benign lesions. Methods A total of 106 patients with benign vocal cord lesions undergoing microsurgery under general anesthesia for the first time in the department of otolaryngology of a tertiary A hospital in Tianjin from April 2020 to March 2021 were selected and divided into an experimental group and a control group by random number table method,with 55 patients in the experimental group and 53 patients in the control group. The experimental group was given four-part correction rehabilitation training on the basis of routine nursing,and the control group received routine nursing program. The voice handicap index and multidimensional voice analysis were used for evaluation. The voice impairment index (VHI) and acoustic parameters (NHR),Shimmer,Jitter and MPT were compared and analyzed on the day of admission,the day of discharge,2 weeks and 4 weeks after surgery. Results There was no statistical significance in NHR,Shimmer,Jitter,MPT and VHI values on the day of admission and discharge between the 2 groups (P>0.05). The data of 2 weeks and 4 weeks after surgery were compared between the 2 groups,and the NHR,Shimmer,Jitter and VHI values of the experimental group were lower than those of the control group,while the MPT value was higher. The differences between the 2 groups were statistically significant (P<0.05). Conclusion Four-part correction rehabilitation training can effectively improve the subjective feeling and voice quality of patients with voice disorders after surgery for benign vocal cord lesions,help to change patients’ bad voice habits and behaviors,and promote the rehabilitation of patients.