中华护理杂志 ›› 2021, Vol. 56 ›› Issue (8): 1201-1207.DOI: 10.3761/j.issn.0254-1769.2021.08.013
收稿日期:
2021-02-25
出版日期:
2021-08-15
发布日期:
2021-08-16
作者简介:
文翠菊:女,硕士,主管护师,E-mail: WEN Cuiju(),WANG Yueni,SUN Hongjuan,YU Xinying
Received:
2021-02-25
Online:
2021-08-15
Published:
2021-08-16
摘要: 目的 探讨乳腺癌患者在接受芳香化酶抑制剂(aromatase inhibitor,AI)治疗期间所出现的症状群及生活质量,并分析症状群与生活质量的相关性。方法 采取横断面调查,选取2020年4月—2021年1月就诊于北京市某肿瘤专科医院乳腺中心门诊患者260例。采用一般情况调查表、安德森症状量表、简明健康调查量表进行调查。 结果 回收有效问卷254份。通过主成分分析,提炼出3组症状群:病感症状群、治疗相关-心理症状群、消化系统症状群。患者简明健康调查量表生理健康、心理健康得分分别为(38.51±12.03)分、(43.06±14.29)分。多元线性回归分析显示,病感症状群越重、治疗相关-心理症状群越重、体重指数越高、文化程度越低,患者的生理健康越差;随着口服AI时间的延长,生理健康会有所改善。治疗相关-心理症状群越重,则患者的心理健康越差。 结论 乳腺癌患者在接受AI治疗期间存在多组症状群,症状群与生活质量呈负相关。医护人员应关注接受AI治疗患者,有必要制订针对性的干预措施,以缓解症状群并改善患者的生活质量。
文翠菊,王玥妮,孙红娟,于新颖. 芳香化酶抑制剂治疗期间乳腺癌患者症状群对生活质量的影响[J]. 中华护理杂志, 2021, 56(8): 1201-1207.
WEN Cuiju,WANG Yueni,SUN Hongjuan,YU Xinying. Symptom clusters and the effects on quality of life among breast cancer patients receiving aromatase inhibitors[J]. Chinese Journal of Nursing, 2021, 56(8): 1201-1207.
表1 调查对象的一般资料和生活质量单因素分析结果(n=254)
Table 1 The demographic and clinical characteristics of the participants and the results of the univariate analysis of the quality of life(n=254)
表3 芳香化酶抑制剂治疗期间患者症状群与生活质量相关性分析(n=254)
Table 3 The correlation analysis of the symptom clusters and quality of life during the aromatase inhibitor adjuvant treatment(n=254)
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