关键词: 衰弱, 慢性阻塞性肺疾病, 健康结局, 系统评价, 护理

Abstract:

Objective To systematically evaluate the effects of frailty on adverse health outcomes in patients with chronic obstructive pulmonary disease（COPD）. Methods Several electronic databases（Pubmed,Web of Science,Wiley Online Library,Cochrane Library,EBSCO host,CINAHL,Springer Link,Scopus,CNKI,WanFang data,CBM and VIP） were searched from inception to August 2019,in order to collect relevant English or Chinese studies examining the association between frailty and at least one health outcome of COPD patients. The quality appraisal was conducted using NOS scale or AHRQ scale according to research type. Results A total of 12 studies involving 4 196 patients were adopted,including 7 cohort studies and 5 cross-sectional studies. Descriptive analysis of the systematic review was conducted according to the Integral Conceptual Model of Frailty proposed by Gobbens et al. Results shows that frailty is significantly associated with an increased risk of disability,decreased quality of life,increasedutilization of healthcare resources and increased risk of death. Conclusion Based on the systematic review,frailty is closely associated with a variety of adverse health outcomes in COPD patients. Therefore,domestic scholars should pay more attention to frailty. Early assessment,early identification and early intervention in frailty can help to prevent or delay the progression of frailty,which is of great significance to improve the health outcomes of COPD patients.

Key words: Frailty, Chronic Obstructive Pulmonary Disease, Health Outcomes, Systematic Review, Nursing Care