关键词: 运动疗法, 胃癌, 化疗, 癌因性疲乏, 重复测量方差分析, 护理

Abstract:

Objective To explore the effects of different walking exercises on cancer-related fatigue in patients with gastric cancer during chemotherapy.Methods The convenience sampling method was adopted to select 124 patients with gastric cancer chemotherapy admitted to a tertiary tumor hospital in Fujian Province from November 2018 to June 2019 as the research subjects. According to the bed management of the medical group,they were divided into a primary group,an intermediate group,an advanced group and a control group with 31 cases in each group. The primary,intermediate and advanced groups need to meet daily walking exercise requirements on the basis of routine care. Among them,the primary group is 5 000-7 499 steps/d;the intermediate group is 7 500-9 999 steps/d;the advanced group is ≥10 000 steps/d. The control group was given routine care and exercise education. The Chinese version of the Revised Piper Fatigue Scale（RPFS） was used for the assessment before the first chemo-therapy,the third,the fifth and the seventh admission to the hospital.Results Repeated measures analysis of variance showed that the RPFS scores of the primary,intermediate,and advanced groups were lower than those of the control group at different time points after the intervention,and the differences were statistically significant（P<0.05）;at the third chemotherapy,there was no statistically significant difference in RPFS scores among the primary,intermediate,and the advanced group（P>0.05）;during the 5th and 7th chemotherapy,the RPFS scores of the primary and intermediate groups were lower than those of the advanced group,and the differences were statistically significant（P<0.001）.Conclusion Walking exercise can reduce the severity of cancer-related fatigue in patients with gastric cancer during chemotherapy. During the first to third chemotherapy sessions,patients should be encouraged to walk ≥5 000 steps/d,and during the fourth to seventh chemotherapy sessions,it should be controlled at 5 000-9 999 steps/d.

Key words: Exercise Therapy, Gastric Cancer, Chemotherapy, Cancer-Related Fatigue, Repeated Measurement Analysis of Variance, Nursing Care