关键词: 非药物干预, 乳腺肿瘤, 抑郁, 睡眠, 生活质量, Meta分析, 康复护理

Abstract:

Objective To assess and compare effectiveness of non-pharmacological interventions on depression,sleep,and quality of life in breast cancer survivors. Methods The published literature that correlated with non-pharmacological interventions in breast cancer survivors in PubMed,Web of Science,MEDLINE,Embase,CNKI,Wanfang,CBM and VIP were collected. With formulated inclusion and exclusion criteria,the literature was screened,and the information was extracted;the bias risk assessment tools of Review Manager 5.3 were applied in the quality evaluation of these documents;the network relations among the studies were performed by STATA 15.0,thereby the publication bias was analyzed. The measurement of convergence was conducted;the Bayesian models were established;the probabilities of the interventions to become the best one were performed by the area under curve in the accumulative ranking probability chart. Results An amount of 22 available documents referring to 2,739 breast cancer survivors were included in this study,and we have found cognitive behavioral therapy to be the best intervention of improving depression,sleep and quality of life with the probabilities of 72%,59% and 41%. Conclusion Cognitive behavioral therapy has the best effect on the improvement of depression,sleep,and quality of life in patients with breast cancer in convalescence. It can be preferred in care intervention on breast cancer survivors.

Key words: Non-Pharmacological Intervention, Breast Neoplasms, Depression, Sleep, Quality of Life, Meta-Analysis, Rehabilitation Nursing