关键词: 白血病，急性, 主要照顾者, 用药安全, 体验, 质性研究, 儿科护理学

Abstract:

Objective To explore primary caregivers’ experience of engagement for medication safety for acute leukemia children with chemotherapy，and to provide bases for formulating targeted interventions. Methods In December 2022，the purposive sampling was used to select 11 primary caregivers of children under 12 with acute leukemia in a tertiary A general hospital in Guangzhou. Semi-structured interviews were held based on the Ladder of Patient and Family Engagement framework. Colaizzi's seven-step method was used for data analysis. Results 4 main themes and 9 sub-themes were identified，including lack of information on chemotherapy medication（lack of knowledge of disease-related medication and insufficient access to medication information），inadequate effective communication of medication information（poor communication with healthcare professionals and limited communication content among caregivers），low level of participation in medication safety（lack of energy to participate，single participation behavior，and limited participation strategies），and inadequate equal participation in medication safety（over-reliance on healthcare professionals and lack of opportunities for deep participation）. Conclusion Primary caregivers’ degree of engagement for chemotherapy medication safety in their children with acute leukemia is relatively low. Interventions should be taken to improve caregivers’ knowledge of their children's medication，facilitate involvement of healthcare professionals and patients and caregivers，empower caregivers to ensure their full participation in their children's medication safety.

Key words: Leukemia，Acute, Primary Caregivers, Medication Safety, Experience, Qualitative Research, Pediatric Nursing