Chinese Journal of Nursing ›› 2023, Vol. 58 ›› Issue (5): 609-616.DOI: 10.3761/j.issn.0254-1769.2023.05.015

• Evidence Synthesis Research • Previous Articles     Next Articles

Summary of best evidence for management of fatigue in patients with hematopoietic stem cell transplantation

CHEN Jingyi(), HU Rong(), WANG Binbin, LI Zhangjie   

  • Received:2022-05-09 Online:2023-03-10 Published:2023-03-01
  • Contact: HU Rong

造血干细胞移植患者疲乏管理的最佳证据总结

陈婧怡(), 胡荣(), 王滨滨, 李张杰   

  1. 350122 福州市 福建医科大学护理学院
  • 通讯作者: 胡荣
  • 作者简介:陈婧怡:女,硕士(博士在读),E-mail:jingyichen1992@126.com
  • 基金资助:
    福建省科技创新联合资金项目(2019Y9029)

Abstract:

Objective To retrieve,evaluate and summarize domestic and foreign available evidence on the management of fatigue in patients with hematopoietic stem cell transplant(HSCT),so as to provide references for clinical evidence-based practice. Methods We systematically searched domestic and foreign computer decision support systems,guideline websites,databases,and relevant society websites for evidence on the management of fatigue in patients with HSCT,including guidelines,clinical decision-making,recommended practices,evidence summaries,systematic reviews,and expert consensuses published from the establishment of the databases or websites to February 10,2022. There were 2 researchers who evaluated the quality of the included literature independently,and combined the professional judgement with information extraction. Results A total of 24 pieces of literature were eligible for inclusion,including 4 clinical guidelines,2 evidence summaries,1 expert consensus and 17 systematic reviews. There were 24 pieces of best evidence with 8 dimensions being summarized,namely assessment,exercise management,psychosocial interventions,health education,nutritional therapy,complementary and alternative therapies,rational drug use,and shared decision-making and multidisciplinary collaboration. Conclusion Nursing staff should pay attention to the management of fatigue in patients with HSCT,and manage patients’ fatigue in a standardized,effective,and safe way according to characteristics of clinical environment and patients’ preferences,so as to improve their prognosis and quality of life.

Key words: Hematopoietic Stem Cell Transplantation, Fatigue, Evidence Summary, Evidence-Based Nursing

摘要:

目的 检索、评价并总结国内外关于造血干细胞移植患者疲乏管理的最佳证据,为临床开展相关循证护理实践提供参考。 方法 系统检索国内外计算机决策支持系统、指南网站、数据库、相关专业协会网站中关于造血干细胞移植患者疲乏管理的证据,包括指南、临床决策、推荐实践、证据总结、系统评价及专家共识。检索时间为建库至2022年2月10日。由2名研究者独立对文献质量进行评价,并结合专业判断进行资料提取、整合。 结果 共纳入24篇文献,其中指南4篇、专家共识1篇、证据总结2篇、系统评价17篇。总结的最佳证据包括疲乏的评估、运动管理、心理社会干预、健康教育、营养管理、补充和替代疗法、合理用药、共同决策和多学科合作8个方面,共24条。 结论 临床护理人员需要重视造血干细胞移植患者的疲乏管理,应根据临床实际情况和患者意愿,以规范、有效、安全的方式管理疲乏,以改善其预后和生活质量。

关键词: 造血干细胞移植, 疲乏, 证据总结, 循证护理学