中华护理杂志 ›› 2023, Vol. 58 ›› Issue (12): 1496-1503.DOI: 10.3761/j.issn.0254-1769.2023.12.013
王伊娜(), 徐亦虹, 柳小琳, 吴文瑾, 颜梦雅, 王美娟, 高杨, 杨丹, 潘红英(), 徐菊玲
收稿日期:
2022-07-20
出版日期:
2023-06-20
发布日期:
2023-06-25
通讯作者:
潘红英,E-mail:panhy@srrsh.com作者简介:
王伊娜:女,本科(硕士在读),护士,E-mail:wangyina2020@163.com
基金资助:
WANG Yina(), XU Yihong, LIU Xiaolin, WU Wenjin, YAN Mengya, WANG Meijuan, GAO Yang, YANG Dan, PAN Hongying(), XU Juling
Received:
2022-07-20
Online:
2023-06-20
Published:
2023-06-25
摘要:
目的 系统地检索和评价肝切除术后患者肝功能衰竭的风险预测模型,旨在为构建更高质量的肝切除术后患者肝功能衰竭的风险预测模型提供参考。 方法 检索中国知网、万方数据库、中国生物医学文献数据库、PubMed、Web of Science、Embase、Cochrane Library、CINAHL数据库中有关肝切除术后患者肝功能衰竭风险预测模型构建的研究,检索时限为建库至2022年2月26日,由2名研究者独立筛选文献,并根据预测模型研究数据提取表和偏倚风险评估工具进行资料提取以及评价纳入文献的偏倚风险和适用性。 结果 共纳入18项肝切除术后患者肝功能衰竭风险预测模型的构建研究,涉及21个模型,受试者工作特征曲线下面积为0.690~0.883。模型重复报告的独立预测因子为总胆红素浓度、剩余肝脏体积、血小板计数、凝血酶原时间、白蛋白浓度、肝硬度、肝切除范围。尚有争议的预测因子为男性、腹腔镜手术、肝-肌比率。纳入研究的偏倚风险均较高,主要原因是样本量不足、连续性变量处理方式不合理、缺乏模型性能评估以及模型过度拟合等。 结论 现有的肝切除术后患者肝功能衰竭风险预测模型尚处于发展阶段,预测因子存有一定共性与争议,未来可开展模型的验证研究或开发性能优良的本土化预测模型。
王伊娜, 徐亦虹, 柳小琳, 吴文瑾, 颜梦雅, 王美娟, 高杨, 杨丹, 潘红英, 徐菊玲. 肝切除术后患者肝功能衰竭风险预测模型的系统评价[J]. 中华护理杂志, 2023, 58(12): 1496-1503.
WANG Yina, XU Yihong, LIU Xiaolin, WU Wenjin, YAN Mengya, WANG Meijuan, GAO Yang, YANG Dan, PAN Hongying, XU Juling. A systematic review of risk prediction models for liver failure after hepatic resection[J]. Chinese Journal of Nursing, 2023, 58(12): 1496-1503.
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