中华护理杂志 ›› 2022, Vol. 57 ›› Issue (3): 348-355.DOI: 10.3761/j.issn.0254-1769.2022.03.016
收稿日期:
2021-06-07
出版日期:
2022-02-10
发布日期:
2022-01-24
作者简介:
李乾:男,硕士,护师,E-mail: 2423429968@qq.com
LI Qian(), ZHAO Xin, ZHANG Xiaowei, LU Huapeng, JIA Bei, CHENG Yan
Received:
2021-06-07
Online:
2022-02-10
Published:
2022-01-24
摘要:
目的 系统评价国内成人肿瘤患者PICC相关性血栓的发生率。方法 计算机检索PubMed、Embase、The Cochrane Library、Web of Science、中国生物医学文献数据库、中国知网、万方数据库和维普数据库,收集关于国内成人肿瘤患者PICC相关性血栓发生率的文献,检索时限为建库至2021年5月。2名研究者独立筛选文献、提取资料并评价纳入文献的偏倚风险后,采用Stata 14.0软件进行Meta分析。 结果 共纳入23篇文献,包括15 066例肿瘤患者。Meta分析结果显示,国内成人肿瘤患者PICC相关性血栓的发生率为8.82%[95%CI(5.93%~12.18%)]。亚组分析结果显示,发表年份为2019年—2021年的文献、年龄≥60岁、BMI>25、穿刺静脉为头静脉、穿刺方法为传统方法、穿刺次数>1次、导管规格为5 Fr、肺癌、肿瘤分期为Ⅲ~Ⅳ期、合并糖尿病、有PICC置管史、有静脉血栓史、置管前纤维蛋白原 ≥4 g/L、置管前D-二聚体≥0.5 mg/L的患者PICC相关性血栓发生率更高。 结论 成人肿瘤患者PICC相关性血栓的发生率较高,医护人员应重视高危患者的早期筛查和相关预防工作。
李乾, 赵欣, 张晓维, 鲁华鹏, 贾蓓, 程言. 国内成人肿瘤患者PICC相关性血栓发生率的Meta分析[J]. 中华护理杂志, 2022, 57(3): 348-355.
LI Qian, ZHAO Xin, ZHANG Xiaowei, LU Huapeng, JIA Bei, CHENG Yan. Incidence of peripherally inserted central catheter-related thrombosis in Chinese adult cancer patients:a meta-analysis[J]. Chinese Journal of Nursing, 2022, 57(3): 348-355.
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