Objective To explore the current status and latent classes of the chemotherapy related symptom cluster of lung cancer patients，and to analyze the differences in 4 aspects of society，disease，physiology and behavior among different classes. Methods Through convenience sampling，lung cancer patients undergoing chemotherapy were recruited from a tertiary hospital in Guangzhou from October 2020 to November 2021. Basic Information Questionnaire，International Physical Activity Questionnaire-Short Form，Exercise Self-Efficacy Scale，Chinese Version of Brief Fatigue Inventory，Athens Insomnia Scale，Chinese Version of Brief Pain Inventory and Patient Health Questionnaire-9 were used for investigation. Exploratory latent class analysis（LCA） was performed by Mplus 8.3. SPSS 25.0 was applied for univariate analysis and logistic regression to identify the factors influencing the latent classes. Results 294 effective questionnaires were collected，and the effective recovery rate was 91.88%. There were 84.4% of lung cancer patients with chemotherapy related symptom cluster，which could be divided into a “high symptom group”（53.6%） and a “low symptom group”（46.4%） by latent class analysis. Logistic regression analysis showed that work status，BMI，physical activity，exercise self-efficacy，time of diagnosis and albumin were the influencing factors of latent classes of symptom cluster in lung cancer patients undergoing chemotherapy. Conclusion The chemotherapy related symptom cluster of lung cancer patients are heterogeneous and can be divided into 2 latent classes. Patients who are unemployed，have the BMI<18.5，and have low physical activity，exercise self-efficacy，and albumin levels are more likely to be in the “high symptom group”.

Objective An infusion drip counter is designed,and its application effect is evaluated. Methods An infusion drip counter was self-developed,and it consists of infusion set buckle,display,start/mode switch button,battery,buzzer,infrared sensor area,etc. In the laboratory,the infusion drip rate measured by the drip counter was compared with the infusion drip rate set by the infusion pump,in order to evaluate the accuracy of the counter. Convenience sampling method was used to recruit 200 emergency patients with infusion admitted from March to May 2020 in a tertiary hospital,and they were divided into an experimental group (n=103) and a control group (n=97) according to the seat number during the infusion. The experimental group used the drip counter for counting,and the control group used the manual counting for counting. The difference between the predicted infusion completion time and the actual infusion completion time was compared,as well as the incidence of the intravenous infusion complications such as phlebitis,extravasation,tube blockage,blood return,and the patient satisfaction rate in the 2 groups. The satisfaction rate of nurses using the drip counter was evaluated. Results In the laboratory test,the accuracy of the drip rate counting of this counter was 99.6%,and the drip rate displayed by the counter was compared with the drip rate set by the infusion pump,and the difference was not statistically significant (P=0.829). In the process of clinical application,the difference between the predicted infusion completion time and the actual infusion completion time of the experimental group was smaller than that of the control group;the incidence of blood return was lower than that of the control group;the patient satisfaction rate was higher than that of the control group;the differences were statistically significant (P<0.05). The satisfaction rate of nurses was 96.1%. Conclusion The infusion drip counter has high counting accuracy. The use of this drip counter is beneficial to control the infusion drip rate,reduce the incidence of blood return,and improve the patient’s satisfaction rate.

The nursing key points of a premature infant with acute renal failure undergoing modified continuous drainage and peritoneal dialysis were summarized. Key points:the central venous（double cavity）catheter was selected for continuous drainage;plugging and serious complications were prevented by squeezing drainage tube at fixed time and observing aseptic technique. Lactate peritoneal dialysate heated by infusion thermostats and the controlled infusion speed and body temperature were chose to prevent hypothermia. Abdominal symptoms,input and output of dialysate and urine,and other aspects were closely observed and recorded on a tabular nursing record sheet. Feeding care and the prevention of serious complications were intensified and managed. The infant,underwent 7 days peritoneal dialysis of 20 days in the hospital,recovered smoothly with satisfaction by telephone follow-up.

To summarize the risk assessment and nursing highlights of postoperative hyperperfusion syndrome in 65 patients with carotid artery occlusion surgery. By establishing a risk assessment management team,summarizing high-risk factors,formulating risk assessment form,patients were evaluated and classified into different levels. Nursing highlights included strengthening the risk management of patients with high-risk,improving early warning consciousness,implementing three-level blood pressure management method to control blood pressure,and the close observation of the patients. Under the above risk assessment and nursing care,the incidence of high perfusion syndrome was 3.08%,which was lower than the reported 5.4%. All the patients were discharged with full recovery.